Senior Scientist, Data Scientist Biologics

Merck
Posted on

Type

Executive / senior industry position

A career with EMD Serono is an ongoing journey of discovery: our 58,000 people are shaping how the world lives, works and plays through next generation advancements in Healthcare, Life Science and Electronics. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. EMD Serono is a business of Merck KGaA, Darmstadt, Germany.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Your role:

At EMD Serono in Billerica, MA, our global Computational Chemistry and Biologics group is seeking a data scientist for biologics (NBEs) to develop predictive and generative models for biologics design, computational characterization, and optimization. These predictive models will be used to advance our innovative and dynamic preclinical portfolio.

The Sr. Scientist will join a global team of highly motivated, cross-disciplinary scientists. You will collaborate and work with leading academic research groups in the field of machine and deep learning. In this role you will support biologics discovery working closely with wet-lab biologists and chemists, and software developers within Discovery & Development Technologies in on-going drug discovery projects thereby driving our efforts to identify and optimize innovative oncology and immunology drugs.

Responsibilities:

  • Develop and implement machine-learning and deep-learning based predictive models to characterize NBEs
  • Develop and drive development of our web-based biologics modelling platform
  • Collaborate closely with colleagues from antibody technology, biology, chemistry, and research informatics to shape next-generation antibody design tools
  • Leverage protein sequence and structural information to predict and optimize biophysical properties of biologics
  • Contribute to external collaborations and partnerships

Who you are:

Minimum Qualifications:

  • PhD in Biochemistry, Chemistry, Bioinformatics, Computer Science, Computational Biology, or related discipline
  • 2+ years’ experience with programming skills in languages like Python or R
  • 2+ years’ experience in computational methods with an emphasis on design and optimization of biologics sequences and properties

Preferred Qualifications:

  • 2+ years of drug discovery experience in academia or pharmaceutical/biotech industry
  • 2+ years’ experience in scientific software development
  • 1+ years’ experience with machine-learning and deep-learning libraries such as scikit-learn, TensorFlow, PyTorch
  • Experience in analyzing protein sequences and applying structural biology methods for design and optimization of biologics (protein homology modeling and simulation, affinity prediction, prediction of biophysical biologics properties)
  • Experience with antibody, nanobody or large molecules screening and production technologies
  • Good understanding of laboratory techniques in molecular biology, biophysical and cellular assays and Next-generation sequencing, protein expression and purification
  • Evidence of creative application of computational approaches to problems of pharmaceutical interest.
  • Track record of publications and presentations.
  • Sound understanding of database handling and web applications
  • Ability to work well in multidisciplinary teams
  • Curious mindset with a can-do mentality
  • Excellent communication, presentation, and collaboration skills

RSRSO

What we offer: With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!

Curious? Apply and find more information at https://jobs.vibrantm.com

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

More Information

Posted on

Type

Executive / senior industry position

Billerica%2C%20US%2C%20Billerica%2C%20United%20States

Billerica, US

Billerica , United States