Notice of Intent to Publish a Funding Opportunity Announcement for Mechanistic links between diet, lipid metabolism, and tumor growth and progression (R01 Clinical Trial Not Allowed)

The National Cancer Institute (NCI) intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) with special receipt, referral, and/or review conditions (PAR) inviting R01 applications for Research Projects that identify and define the mechanisms that link diet with lipid metabolism-mediated tumor growth and progression. This proposed funding announcement has three goals: one, to support fundamental studies designed to identify and define the molecular mechanisms through which lipid metabolism mediates tumor growth and progression, focusing specifically on the central role lipids play in linking diet with the biology of cancer; two, bridge the historically divided fields of nutrition and molecular metabolism; and three, stimulate research and tool development in this emerging area, which faces particular challenges because of the complexity of lipid biochemistry. This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. To ensure appropriate expertise in nutrition, all applicants are encouraged to include a co-Investigator or use an MPI structure; applications that fail to include appropriate expertise in nutrition and/or do not propose fundamental, mechanistic investigations will be considered non-responsive. Furthermore, applications that include collaborators from fields outside of cancer research are particularly encouraged. The FOA is expected to be published in Late Summer 2022 with an anticipated application due date in Fall 2022.
Categories: Health.