Investigating the Effects of Addictive Substances on Brain Developmental Trajectories Using Innovative Scalable Methods for Quantification of Cell Identity, Lineage and Connectivity (R01 - Clinical Trial Not Allowed)
Department of Health and Human Services National Institutes of Health
Type
Research/project funding
Posted on:
Application Deadline:
Expired
Reference Number
RFA-DA-23-036
This Funding Opportunity Announcement (FOA) will support projects that investigate the effects of addictive substances on developmental trajectories of molecularly-defined CNS cells and circuits. Emphasis is on carrying out systematic and highly granular quantitative characterizations of the impact of in utero and/or postnatal substance exposure on the numbers, spatial distribution and connectivity of molecularly-defined cells, across whole brains or within distributed circuits of clinical relevance. The ultimate goals of the program are to identify critical developmental windows and cellular mechanisms mediating the protracted developmental impact of addictive substances, and will inform clinical practice, by complementing the data from human longitudinal neuroimaging studies such as the ABCD study.?
Categories: Education, Health.
Categories: Education, Health.
United States