Research Network to Promote Multidisciplinary Mechanistic and Translational Studies of Sickle Cell Disease Pain (U24, Clinical Trial Optional)

The purpose of this FOA is to support a Research Network that promotes multidisciplinary mechanistic and translational studies of Sickle Cell Disease (SCD) pain. This network is expected to develop compelling research frameworks and model systems that will support interdisciplinary collaborations; initiate pilot projects to test novel mechanistic hypotheses in the high-priority research areas listed below and develop novel technologies and methodologies to study pain in the organ(s) typically impacted by SCD. To accomplish these objectives, applicants can propose activities such as meetings, workshops, conferences, research collaborations, exchange of ideas through visiting scientist arrangements, or training opportunities. These activities will help identify unique research gaps and opportunities that can be addressed through the network in the form of pilot projects which will in turn generate the preliminary data needed for SCD pain investigators to successfully compete for more substantial NIH grants, including The Helping to End Addiction Long-term (HEAL) Initiative grant awards. In addition, the network shall sustain its scientific impact through a variety of dissemination and outreach strategies, including publication of research frameworks, reviews, and other best practices to foster the growth and development of research in priority areas.
Categories: Health.