HEAL Initiative: NIH-DOD-VA Pain Management Collaboratory Pragmatic and/or Implementation Science Demonstration Projects ((UG3/UH3) Clinical Trial Required)

Funding Opportunity RFA-AT-24-011 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to solicit UG3/UH3 phased award research applications to conduct efficient, large-scale pragmatic clinical trial and/or implementation science Demonstration Projects within the infrastructure of the NIH-DoD-VA Pain Management Collaboratory (PMC) on non-opioid approaches to pain management and other comorbid conditions in U.S. veterans, military personnel, and their families. Additional emphasis on a whole person approach to pain management will be added as a priority for NCCIH and partnering ICOs will also add their priority areas that include pain. This NOFO will add a trial supported by the HEAL Initiative, an NIH-wide research effort aimed at addressing the opioid epidemic in part by identifying effective, non-opioid pain management solutions. The PMC established a Coordinating Center in 2017 that provides national leadership and technical expertise for all aspects of PMC research including assistance to Demonstration Project grant awardees.