HEAL Initiative - Sleep Predictors of Opioid-Use Disorder Treatment Outcomes Program: Leadership and Data Co-ordinating Center (U01 Clinical Trial Optional)

Funding Opportunity RFA-DA-23-060 from the NIH Guide for Grants and Contracts. Applications are invited from institutions to participate as the Leadership and Data Coordinating Center (LDCC) for the Sleep Predictors of Opioid Use Disorders (OUD) Treatment and Outcomes Program. The overall goals of this program are a) to uncover novel mechanisms underlying the bidirectional interrelationship between sleep/circadian rhythm and OUD, and b) to delineate sleep and/or circadian-based predictors of OUD treatment response and outcomes. The Leadership and Data Coordination Center will lead, coordinate and analyze data for a multi-site common protocol focused on sleep/circadian rhythm measures. The data will be used to develop a predictive model of OUD medication treatment response and outcomes.