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Funding Opportunity RFA-DA-26-016 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) proposing research and development of medical devices specifically indicated for pediatric population (i.e., 0-21 years old, as defined by the FDA Center for Devices and Radiological Health) affected by substance use and addiction.